Emily K Burr

Research topics

Matched from this investigator's NIH project titles and abstracts.

• Eating Disorders
• Emotion and Affective Neuroscience
• Addiction and Substance Use

Active NIH awards

• Applying Harm Reduction to Binge Eating Disorder: An Investigation of Protective Behavioral Strategies Against Uncontrolled Eating

  1F31MH135713-01A1

  NIMH · FY 2024 · $38K

  PROJECT SUMMARY/ ABSTRACT Binge eating disorder (BED) is the most diagnosed eating disorder, characterized by eating objectively large amounts of food one feels unable to refrain from or stop consuming (i.e., binge eating; BE). Recurrent BE must be present at least once a week on average over the past three months and co-occur with significant psychological distress. BED is notoriously difficult to treat, with some estimates concluding that more than one half of patients do not maintain remission from binge eating six months after treatment discontinuation. BE is often onset by momentary factors, such as a desire to reduce negative affect, or as a response to food cravings. Less understood is what differentiates individuals with BED and those without eating pathology when experiencing cravings or negative affect, and if there are strategies that prevent BE for the latter population. Increasingly, there has been a call for assessment of the efficacy of a harm reduction approach in addressing eating disorders. Harm reduction, primarily utilized in the substance use disorder field, is a framework in which lowering risk of use is promoted in those who are unable or unwilling to completely abstain from a harmful behavior. Experiences shared across substance use disorders and binge eating (e.g., cravings) may account for the high co-occurrence of BED and substance use, and salience of similar treatment targets and intervention strategies. Protective behavioral strategies (PBS) are actions one can take while engaging in a potentially harmful behavior to decrease risk of serious consequences. Characteristics of highly palatable foods (e.g., high sugar/ fat) and frequency at which they are consumed are associated with serious morbidity and mortality implications, and thus these foods are commonly recognized as risky to over-consume. The proposed study will utilize a PBS framework to assess how PBS may apply to reducing the frequency and intensity of BE and specifically, whether there are differences between healthy controls (HC) and individuals with BED regarding their momentary-level behavior that leads to differential eating outcomes. First, using an online screener to recruit from a national sample, an estimated 10-15 HC and 10-15 individuals with BE will engage in interviews to qualitatively assess presence of BE and eating-related PBS (Aim 1). Next, a measure of eating-related PBS will be developed from qualitative responses and cognitive interviews will be used to refine and ascertain comprehension of the developed measure. The measure will then be validated among 500 with BE and 500 HC in an online survey (Aim 2). Finally, 25 HC and 25 individuals with BED will participate in an ecological momentary assessment study where they report daily-level PBS to assess for group differences in PBS use in response to real-life BE precedents (Aim 3). The proposed study will implement a mixed methods approach utilizing technology for real-time assessment to investigate PBS against BE. Findings will inform potential efficacy of PBS for eating behavior in line with a harm reduction approach and may bolster existing BED interventions.